Welcome to the Marianski Group at Hunter College
Who we are and what we do:
We are computational chemists - computational chemistry gives us an unparalleled ability to visualize, with atomic – or even electronic – resolution, the mechanistic underpinning of physical, chemical, and biochemical processes, and in effect, provide a crucial insight into most challenging questions in the development of novel therapeutic strategies, and chemical synthesis.
Our research is focused around five main areas, three of which are connected by the theme of carbohydrates: 1) Mechanochemistry: Altering chemical reactions with a mechanical force; 2) Glycosylation: Improving stereocontrol of a glycosylation reaction; 3) Glycoanalysis: Understanding structure-function relationship in glycans; 4) Site-specific biolabeling: Designing new generation of site-specific labels of IgGs; and 5) Antivirals: Exploiting glycans as a target for novel antivirals.
News from the lab:
03/12/2024: New review on kinectics of covalent-bond forming reactions under mechanochemical conditions just got published in the first issue of RSC Mechanochemistry journal
12/09/2023: Congratulations to Ryan for winning the Schectman Award at the Chemistry Department for the best 1st-year graduate student.
12/08/2023: Congratulations to Ryan for winning the NanoBioNYC student award for outstanding research and a great popularization of his science!
12/07/2023: New publication on unexcpected selectivity of glycosylation of 2-deoxy sugars had appeared in Organic Letters! Congratulations to Ryan for contributing to this work.
11/13/2023: New publication on conformational stability of S-glucosides has appeared in The Journal of Organic Chemistry! Congratulations to Ryan and Malika for contributing to this work.
10/26/2023: Opportunities for Summer Research Experience for Undergraduate are available - inquire the PI.
08/08/2023: National Science Foundation has creation of the new CCI: Center for the Mechanical Control of Chemistry (CMCC). Full announcement here.
06/08/2023: The paper on “Acceleration of Diels-Alder reaction by Mechanical Distortion” is available online!
05/26/2023: Congratulations to Lusila Vranga, Yusef Wray, and Vasilis Kontodimas for the graduation from the Chem Dept at Hunter with Honors!
05/10/2023: The paper on “Decoding Decoding the Fucose Migration Product during Mass-Spectrometric analysis of Blood Group Epitopes” is available online!
05/02/2023: Prof. Marianski is a receipient of The Henry Wasser 2023 CUNY Award for the Outstanding Research.
04/21/2023: New DoD Grant for development of SCR-based sensors for virus detections has been awarded!
04/19/2023: Congratulations to Murat for winning the 2023 Student Award “Breaking Boundaries Award for Cross Cutting Computational Research” at NanoBioNYC for his work on Fucose migration in Blood Group epitopes!